Arthritis

Osteoarthritis vs Rheumatoid Arthritis: Key Differences

Learn how osteoarthritis and rheumatoid arthritis differ in their causes, typical symptoms and the joints they most often affect.
Older adult's hands resting on their knee, holding a small yellow ball, with a caregiver's hand on their arm

Arthritis is not one disease. Osteoarthritis and rheumatoid arthritis are two of the most common types, and they have different causes.

Osteoarthritis involves the gradual breakdown of the cartilage that cushions joints, and it often affects the hands, knees, hips and spine. Rheumatoid arthritis is an autoimmune condition in which the immune system mistakenly attacks the lining of the joints, and it commonly affects both sides of the body.

  • Osteoarthritis pain often worsens with activity and eases with rest.
  • Rheumatoid arthritis may bring prolonged morning stiffness, swelling and fatigue.
  • Either type can affect daily life, so early assessment matters.

If joint pain, swelling or stiffness keeps returning or lasts more than a few days, talk to your doctor about the right tests and treatment options.

Health information, not medical advice. This article is for general education and does not replace a professional diagnosis or treatment. If you have symptoms or questions about your health, talk to a qualified health provider, and call your local emergency number in an emergency.

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